🚚 GRATIS FRAGT I KUNDEKLUBBEN VED KØB AF MERE END 1 PRODUKT
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Are you concerned about possible side effects of taking red clover or red clover extract while experiencing menopausal symptoms? If you are healthy, there are no reported or known side effects associated with red clover — including the fermented red clover extract used in REGOMEO and REGOBONE from Herrens Mark. Studies from Aarhus University have shown that fermented red clover extract can reduce hot flushes by an average of 23% and sweating tendencies by 40%, as documented in a randomised, placebo-controlled clinical study.
One reason it may seem relevant to discuss side effects of red clover is that red clover naturally contains phyto-oestrogens. Phyto-oestrogens are found in red clover, soya, and hops, among other sources. The phyto-oestrogens in red clover are what make it particularly interesting in relation to menopausal symptoms experienced by some women, such as hot flushes, night sweats, reduced energy, and insomnia.
Red clover has long been associated with menopause, and its isoflavone content may help support a calmer and more comfortable menopausal transition by relieving some of the well-known symptoms. This is because phyto-oestrogens may help balance the natural decline in oestrogen that occurs during and after menopause.
When women go through menopause, oestrogen levels in the body decrease. This low level of oestrogen can affect both the body and mood. Red clover’s phyto-oestrogens, also known as isoflavones, are of interest in this context because they have a structure similar to oestrogen.
The hormone oestrogen binds primarily to different receptors than phyto-oestrogens. Phyto-oestrogens from red clover bind most strongly to the so-called beta receptors in the body (including bones, the brain, kidneys, and lungs), whereas oestrogen binds most strongly to the so-called alpha receptors, which are found in high concentrations in breast and uterine tissue.
So far, no adverse side effects have been observed from phyto-oestrogens used in connection with managing menopausal symptoms.
Many people are cautious about taking hormones, including oestrogen. However, when it comes to phyto-oestrogens, and if you are otherwise healthy, it is considered safe to take red clover. In 2015, The European Food Safety Authority (EFSA) performed the most comprehensive safety assessment of phytoestrogens (isoflavones) to date. In its report, the EFSA confirms that there is no risk for women who take doses of up to 150 mg isoflavone daily. If you would like to find out more about the report from the European Food Safety Authority, please check the links at the bottom of this article. Here you can read both the actual report and a press release issued by the EFSA in connection with the publication of the report.
By way of comparison, the two fermented red clover products from Herrens Mark contain the following quantities of isoflavones: REGOMEO contains min. 33 mg per 60 ml while REGOBONE contains 60 mg per 100 ml. This roughly corresponds to the daily dosage of isoflavones (phytoestrogens) found in a normal diet in Asian countries, which is approx. 20-60 mg/day.
At Herrens Mark, we follow the precautionary principle. More clinical research is needed before final conclusions can be drawn regarding the effects of isoflavone intake in patients who have, or have previously had, oestrogen-sensitive cancer (e.g. breast or ovarian cancer).
For this reason, we always advise former and current patients with oestrogen-sensitive cancers only to consume red clover extract in consultation with their doctor.
REGOMEO and REGOBONE consist of fermented red clover. At Herrens Mark, we hold a patent for the fermentation process. This fermentation process allows the sugar molecule to be split off from the isoflavones during fermentation. As a result, the isoflavones are broken down into forms with higher bioavailability and improved
absorption.
Read the press release about the EFSA report on side-effects here
Read the EFSA report on side-effects here
Fermented red clover is generally well tolerated, but may cause mild digestive discomfort such as loose stomach, bloating or stomach cramps in some people – especially at the beginning, when the intestinal flora may react to the lactic acid bacteria and the active content of the plant.
In case of histamine intolerance, extra attention should be paid, as fermented products (such as wine, cheese, chocolate) can in some cases trigger symptoms such as headache, redness, itching, hives or stomach upset, depending on individual sensitivity.
People with allergies to the legume family (such as red clover, beans, peanuts, soybeans) may experience allergic reactions such as itching in the mouth/throat, skin rash or in rare cases more serious symptoms, and should therefore avoid the product or try it with great caution.
